SCOP 1.73: Domain d2aoca1: 2aoc A:1-99

Lineage for d2aoca1 (2aoc A:1-99)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (230 PDB entries)

8. Domain d2aoca1: 2aoc A:1-99 [127080]
   automatically matched to d1s6sa_
   complexed with 2ao, ace, cl, dms, gol, na, nh2, olt; mutant

Details for d2aoca1

PDB Entry: 2aoc, 1.3 Å

PDB Description: Crystal structure analysis of HIV-1 protease mutant I84V with a substrate analog P2-NC

PDB Compounds: (A:) Pol polyprotein

SCOP Domain Sequences for d2aoca1:

Sequence; same for both SEQRES and ATOM records:

>d2aoca1 b.50.1.1 (A:1-99) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvnvigrnlltqigatlnf

Timeline for d2aoca1:

• d2aoca1 is new in SCOP 1.73
  
• d2aoca1 appears in SCOP 1.75
  
• d2aoca1 appears in the current release, SCOPe 2.08, called d2aoca_