SCOPe 2.05: Domain d2ao6a_: 2ao6 A:

Lineage for d2ao6a_ (2ao6 A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Androgen receptor [63621] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63623] (50 PDB entries)
   Uniprot P10275 671-919

8. Domain d2ao6a_: 2ao6 A: [127068]
   automated match to d1xowa_
   complexed with r18

Details for d2ao6a_

PDB Entry: 2ao6, 1.89 Å

PDB Description: crystal structure of the human androgen receptor ligand binding domain bound with tif2(iii) 740-753 peptide and r1881

PDB Compounds: (A:) Androgen receptor

SCOPe Domain Sequences for d2ao6a_:

Sequence, based on SEQRES records:

>d2ao6a_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknpt
scsrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgk
vkpiyfht

Sequence, based on observed residues (ATOM records):

>d2ao6a_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiatscsrrf
yqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgkvkpiyf
ht

Timeline for d2ao6a_:

• d2ao6a_ first appeared in SCOP 1.73, called d2ao6a1
  
• d2ao6a_ appears in SCOPe 2.04
  
• d2ao6a_ appears in SCOPe 2.06
  
• d2ao6a_ appears in the current release, SCOPe 2.08