SCOPe 2.08: Domain d2amaa_: 2ama A:

Lineage for d2amaa_ (2ama A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Androgen receptor [63621] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63623] (65 PDB entries)
   Uniprot P10275 671-919

8. Domain d2amaa_: 2ama A: [127000]
   automated match to d1e3ga_
   complexed with dht, so4

Details for d2amaa_

PDB Entry: 2ama, 1.9 Å

PDB Description: Crystal structure of human androgen receptor ligand binding domain in complex with dihydrotestosterone

PDB Compounds: (A:) Androgen receptor

SCOPe Domain Sequences for d2amaa_:

Sequence, based on SEQRES records:

>d2amaa_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiackrknpt
scsrrfyqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgk
vkpiyfhtq

Sequence, based on observed residues (ATOM records):

>d2amaa_ a.123.1.1 (A:) Androgen receptor {Human (Homo sapiens) [TaxId: 9606]}
piflnvleaiepgvvcaghdnnqpdsfaallsslnelgerqlvhvvkwakalpgfrnlhv
ddqmaviqyswmglmvfamgwrsftnvnsrmlyfapdlvfneyrmhksrmysqcvrmrhl
sqefgwlqitpqeflcmkalllfsiipvdglknqkffdelrmnyikeldriiatscsrrf
yqltklldsvqpiarelhqftfdllikshmvsvdfpemmaeiisvqvpkilsgkvkpiyf
htq

Timeline for d2amaa_:

• d2amaa_ first appeared in SCOP 1.73, called d2amaa1
  
• d2amaa_ appears in SCOPe 2.07