SCOP 1.73: Domain d2ai2a1: 2ai2 A:3-282

Lineage for d2ai2a1 (2ai2 A:3-282)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.56: Phosphorylase/hydrolase-like [53162] (7 superfamilies)
   core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops

4. Superfamily c.56.2: Purine and uridine phosphorylases [53167] (1 family)
   complex architecture; contains mixed beta-sheet of 8 strands, order 23415867, strands 3, 6 & 7 are antiparallel to the rest; and barrel, closed; n=5, S=8

5. Family c.56.2.1: Purine and uridine phosphorylases [53168] (6 proteins)

6. Protein Purine nucleoside phosphorylase, PNP [53169] (9 species)

7. Species Cow (Bos taurus) [TaxId:9913] [53171] (19 PDB entries)

8. Domain d2ai2a1: 2ai2 A:3-282 [126814]
   automatically matched to d1v48a_
   complexed with 144, mg, p1d, zn

Details for d2ai2a1

PDB Entry: 2ai2, 1.7 Å

PDB Description: Purine nucleoside phosphorylase from calf spleen

PDB Compounds: (A:) purine nucleoside phosphorylase

SCOP Domain Sequences for d2ai2a1:

Sequence, based on SEQRES records:

>d2ai2a1 c.56.2.1 (A:3-282) Purine nucleoside phosphorylase, PNP {Cow (Bos taurus) [TaxId: 9913]}
ngytyedyqdtakwllshteqrpqvavicgsglgglvnkltqaqtfdyseipnfpestvp
ghagrlvfgilngracvmmqgrfhmyegypfwkvtfpvrvfrllgvetlvvtnaagglnp
nfevgdimlirdhinlpgfsgenplrgpneerfgvrfpamsdaydrdmrqkahstwkqmg
eqrelqegtyvmlggpnfetvaecrllrnlgadavgmstvpevivarhcglrvfgfslit
nkvimdyesqgkanheevleagkqaaqkleqfvsllmasi

Sequence, based on observed residues (ATOM records):

>d2ai2a1 c.56.2.1 (A:3-282) Purine nucleoside phosphorylase, PNP {Cow (Bos taurus) [TaxId: 9913]}
ngytyedyqdtakwllshteqrpqvavicgsglgglvnkltqaqtfdyseipnfpesgrl
vfgilngracvmmqgrfhmyegypfwkvtfpvrvfrllgvetlvvtnaagglnpnfevgd
imlirdhinlpgfsgenplrgpneerfgvrfpamsdaydrdmrqkahstwkqmgeqrelq
egtyvmlggpnfetvaecrllrnlgadavgmstvpevivarhcglrvfgfslitnkvimd
yesqgkanheevleagkqaaqkleqfvsllmasi

Timeline for d2ai2a1:

• d2ai2a1 is new in SCOP 1.73
  
• d2ai2a1 appears in SCOP 1.75
  
• d2ai2a1 appears in the current release, SCOPe 2.08, called d2ai2a_