SCOPe 2.08: Domain d2ag5b2: 2ag5 B:2-245

Lineage for d2ag5b2 (2ag5 B:2-245)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (319 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186944] (65 PDB entries)

8. Domain d2ag5b2: 2ag5 B:2-245 [126720]
   Other proteins in same PDB: d2ag5a1, d2ag5a2, d2ag5b3
   automated match to d1nffa_
   complexed with nad, so4

Details for d2ag5b2

PDB Entry: 2ag5, 1.84 Å

PDB Description: Crystal Structure of Human DHRS6

PDB Compounds: (B:) dehydrogenase/reductase (SDR family) member 6

SCOPe Domain Sequences for d2ag5b2:

Sequence; same for both SEQRES and ATOM records:

>d2ag5b2 c.2.1.0 (B:2-245) automated matches {Human (Homo sapiens) [TaxId: 9606]}
grldgkviiltaaaqgigqaaalafaregakviatdinesklqelekypgiqtrvldvtk
kkqidqfaneverldvlfnvagfvhhgtvldceekdwdfsmnlnvrsmylmikaflpkml
aqksgniinmssvassvkgvvnrcvysttkaavigltksvaadfiqqgircncvcpgtvd
tpslqeriqargnpeearndflkrqktgrfataeeiamlcvylasdesayvtgnpviidg
gwsl

Timeline for d2ag5b2:

• d2ag5b2 first appeared in SCOP 1.73, called d2ag5b1
  
• d2ag5b2 appears in SCOPe 2.07