SCOPe 2.06: Domain d2ag4b2: 2ag4 B:3-164

Lineage for d2ag4b2 (2ag4 B:3-164)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.95: Ganglioside M2 (gm2) activator [63706] (1 superfamily)
   sandwich; 8 strands in 2 sheets; greek-key: partial topological similarity to immunoglobulin-like folds

4. Superfamily b.95.1: Ganglioside M2 (gm2) activator [63707] (1 family)

5. Family b.95.1.1: Ganglioside M2 (gm2) activator [63708] (1 protein)

6. Protein Ganglioside M2 (gm2) activator [63709] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63710] (8 PDB entries)
   Uniprot P17900 31-193

8. Domain d2ag4b2: 2ag4 B:3-164 [126718]
   Other proteins in same PDB: d2ag4a3, d2ag4b3
   automated match to d1pu5a_
   complexed with ipa, lp3, ola

Details for d2ag4b2

PDB Entry: 2ag4, 1.8 Å

PDB Description: Crystal Structure Analysis of GM2-activator protein complexed with phosphatidylcholine

PDB Compounds: (B:) Ganglioside GM2 activator

SCOPe Domain Sequences for d2ag4b2:

Sequence; same for both SEQRES and ATOM records:

>d2ag4b2 b.95.1.1 (B:3-164) Ganglioside M2 (gm2) activator {Human (Homo sapiens) [TaxId: 9606]}
ssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvlekeva
glwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpkse
fvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi

Timeline for d2ag4b2:

• d2ag4b2 first appeared in SCOP 1.73, called d2ag4b1
  
• d2ag4b2 was called d2ag4b_ in SCOPe 2.05
  
• d2ag4b2 appears in SCOPe 2.07
  
• d2ag4b2 appears in the current release, SCOPe 2.08