SCOPe 2.05: Domain d2aeil2: 2aei L:87-142

Lineage for d2aeil2 (2aei L:87-142)

1. Root: SCOPe 2.05

2. Class g: Small proteins [56992] (92 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (8 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein Coagulation factor VIIa [57201] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57202] (56 PDB entries)
   Uniprot P08709 108-202 ! Uniprot P08709 107-202

8. Domain d2aeil2: 2aei L:87-142 [126633]
   Other proteins in same PDB: d2aeih_, d2aeil3, d2aeit1, d2aeit2
   automated match to d1danl2
   complexed with 03r, ca, cac

Details for d2aeil2

PDB Entry: 2aei, 2.52 Å

PDB Description: Crystal structure of a ternary complex of factor VIIa/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid

PDB Compounds: (L:) Coagulation factor VII

SCOPe Domain Sequences for d2aeil2:

Sequence; same for both SEQRES and ATOM records:

>d2aeil2 g.3.11.1 (L:87-142) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
dqlicvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipile

Timeline for d2aeil2:

• d2aeil2 first appeared in SCOP 1.73
  
• d2aeil2 appears in SCOPe 2.04
  
• d2aeil2 appears in SCOPe 2.06
  
• d2aeil2 appears in the current release, SCOPe 2.08