SCOPe 2.02: Domain d2aeil1: 2aei L:46-82

Lineage for d2aeil1 (2aei L:46-82)

1. Root: SCOPe 2.02

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (7 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein Coagulation factor VIIa [57201] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57202] (35 PDB entries)
   Uniprot P08709 108-202 ! Uniprot P08709 107-202

8. Domain d2aeil1: 2aei L:46-82 [126632]
   Other proteins in same PDB: d2aeih_, d2aeil3, d2aeit1, d2aeit2
   automatically matched to d1pfxl1
   complexed with 03r, ca, cac

Details for d2aeil1

PDB Entry: 2aei, 2.52 Å

PDB Description: Crystal structure of a ternary complex of factor VIIa/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid

PDB Compounds: (L:) Coagulation factor VII

SCOPe Domain Sequences for d2aeil1:

Sequence; same for both SEQRES and ATOM records:

>d2aeil1 g.3.11.1 (L:46-82) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
dgdqcasspcqnggsckdqlqsyicfclpafegrnce

Timeline for d2aeil1:

• d2aeil1 first appeared in SCOP 1.73
  
• d2aeil1 appears in SCOPe 2.01
  
• d2aeil1 appears in SCOPe 2.03
  
• d2aeil1 appears in the current release, SCOPe 2.08