SCOP 1.73: Domain d2aeih1: 2aei H:16-257

Lineage for d2aeih1 (2aei H:16-257)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (33 PDB entries)

8. Domain d2aeih1: 2aei H:16-257 [126631]
   Other proteins in same PDB: d2aeil1, d2aeil2, d2aeil3, d2aeit1, d2aeit2
   automatically matched to d1cvwh_
   complexed with 03r, ca, cac

Details for d2aeih1

PDB Entry: 2aei, 2.52 Å

PDB Description: Crystal structure of a ternary complex of factor VIIa/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid

PDB Compounds: (H:) Coagulation factor VII

SCOP Domain Sequences for d2aeih1:

Sequence; same for both SEQRES and ATOM records:

>d2aeih1 b.47.1.2 (H:16-257) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Timeline for d2aeih1:

• d2aeih1 is new in SCOP 1.73
  
• d2aeih1 appears in SCOP 1.75
  
• d2aeih1 appears in the current release, SCOPe 2.08, called d2aeih_