SCOPe 2.01: Domain d2aclc_: 2acl C:

Lineage for d2aclc_ (2acl C:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Retinoid-X receptor alpha (RXR-alpha) [48510] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48511] (32 PDB entries)
   Uniprot P19793 227-458

8. Domain d2aclc_: 2acl C: [126560]
   Other proteins in same PDB: d2aclb1, d2acld_, d2aclf_, d2aclh_
   automated match to d1lbd__
   complexed with l05, rea

Details for d2aclc_

PDB Entry: 2acl, 2.8 Å

PDB Description: Liver X-Receptor alpha Ligand Binding Domain with SB313987

PDB Compounds: (C:) Retinoic acid receptor RXR-alpha

SCOPe Domain Sequences for d2aclc_:

Sequence, based on SEQRES records:

>d2aclc_ a.123.1.1 (C:) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens) [TaxId: 9606]}
sanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewak
riphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvga
ifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayc
khkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap

Sequence, based on observed residues (ATOM records):

>d2aclc_ a.123.1.1 (C:) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens) [TaxId: 9606]}
sanedmpverileaelavedpvtnicqaadkqlftlvewakriphfselplddqvillra
gwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmd
ktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlp
alrsiglkclehlfffkligdtpidtflmemleap

Timeline for d2aclc_:

• d2aclc_ first appeared in SCOP 1.73, called d2aclc1
  
• d2aclc_ was called d2aclc1 in SCOP 1.75
  
• d2aclc_ appears in SCOPe 2.02
  
• d2aclc_ appears in the current release, SCOPe 2.08