SCOP 1.75: Domain d2aclc1: 2acl C:225-457

Lineage for d2aclc1 (2acl C:225-457)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Retinoid-X receptor alpha (RXR-alpha) [48510] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48511] (18 PDB entries)
   Uniprot P19793 227-458

8. Domain d2aclc1: 2acl C:225-457 [126560]
   Other proteins in same PDB: d2aclb1, d2acld1, d2aclf1, d2aclh1
   automatically matched to d1lbd__
   complexed with l05, rea

Details for d2aclc1

PDB Entry: 2acl, 2.8 Å

PDB Description: Liver X-Receptor alpha Ligand Binding Domain with SB313987

PDB Compounds: (C:) Retinoic acid receptor RXR-alpha

SCOP Domain Sequences for d2aclc1:

Sequence, based on SEQRES records:

>d2aclc1 a.123.1.1 (C:225-457) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens) [TaxId: 9606]}
sanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewak
riphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvga
ifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayc
khkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemlea

Sequence, based on observed residues (ATOM records):

>d2aclc1 a.123.1.1 (C:225-457) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens) [TaxId: 9606]}
sanedmpverileaelavedpvtnicqaadkqlftlvewakriphfselplddqvillra
gwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmd
ktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlp
alrsiglkclehlfffkligdtpidtflmemlea

Timeline for d2aclc1:

• d2aclc1 first appeared in SCOP 1.73
  
• d2aclc1 is called d2aclc_ in SCOPe 2.01
  
• d2aclc1 appears in the current release, SCOPe 2.08, called d2aclc_