SCOPe 2.07: Domain d2abea_: 2abe A:

Lineage for d2abea_ (2abe A:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.74: Carbonic anhydrase [51068] (1 superfamily)
   single sheet; 10 strands

4. Superfamily b.74.1: Carbonic anhydrase [51069] (2 families)

5. Family b.74.1.1: Carbonic anhydrase [51070] (2 proteins)
   automatically mapped to Pfam PF00194

6. Protein Carbonic anhydrase [51071] (10 species)

7. Species Human (Homo sapiens), erythrocytes, isozyme II [TaxId:9606] [51073] (971 PDB entries)
   Uniprot P00918

8. Domain d2abea_: 2abe A: [126518]
   automated match to d1can__
   complexed with hg, his, zn

Details for d2abea_

PDB Entry: 2abe, 2 Å

PDB Description: Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators

PDB Compounds: (A:) carbonic anhydrase II

SCOPe Domain Sequences for d2abea_:

Sequence; same for both SEQRES and ATOM records:

>d2abea_ b.74.1.1 (A:) Carbonic anhydrase {Human (Homo sapiens), erythrocytes, isozyme II [TaxId: 9606]}
hwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnng
hafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvhw
ntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprgl
lpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvdn
wrpaqplknrqikasfk

Timeline for d2abea_:

• d2abea_ first appeared in SCOP 1.73, called d2abea1
  
• d2abea_ appears in SCOPe 2.06
  
• d2abea_ appears in the current release, SCOPe 2.08