SCOP 1.75: Domain d2a9wd1: 2a9w D:1-264

Lineage for d2a9wd1 (2a9w D:1-264)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (1 family)

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (3 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Escherichia coli [TaxId:562] [55834] (52 PDB entries)

8. Domain d2a9wd1: 2a9w D:1-264 [126459]
   automatically matched to d1tlca_
   complexed with 2br, bme, ga9, gol, po4, ump

Details for d2a9wd1

PDB Entry: 2a9w, 1.65 Å

PDB Description: E. coli TS complexed with dUMP and inhibitor GA9

PDB Compounds: (D:) Thymidylate synthase

SCOP Domain Sequences for d2a9wd1:

Sequence; same for both SEQRES and ATOM records:

>d2a9wd1 d.117.1.1 (D:1-264) Thymidylate synthase {Escherichia coli [TaxId: 562]}
mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlk
ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
dyrfedfeiegydphpgikapvai

Timeline for d2a9wd1:

• d2a9wd1 first appeared in SCOP 1.73
  
• d2a9wd1 is called d2a9wd_ in SCOPe 2.01
  
• d2a9wd1 appears in the current release, SCOPe 2.08, called d2a9wd_