SCOPe 2.07: Domain d2a9wa_: 2a9w A:

Lineage for d2a9wa_ (2a9w A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Escherichia coli [TaxId:562] [55834] (71 PDB entries)

8. Domain d2a9wa_: 2a9w A: [126456]
   automated match to d1an5a_
   complexed with 2br, bme, ga9, gol, po4, ump

Details for d2a9wa_

PDB Entry: 2a9w, 1.65 Å

PDB Description: E. coli TS complexed with dUMP and inhibitor GA9

PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d2a9wa_:

Sequence; same for both SEQRES and ATOM records:

>d2a9wa_ d.117.1.1 (A:) Thymidylate synthase {Escherichia coli [TaxId: 562]}
mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlk
ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
dyrfedfeiegydphpgikapvai

Timeline for d2a9wa_:

• d2a9wa_ first appeared in SCOP 1.73, called d2a9wa1
  
• d2a9wa_ appears in SCOPe 2.06
  
• d2a9wa_ appears in the current release, SCOPe 2.08