Lineage for d2a8wa2 (2a8w A:64-345)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2133075Fold c.68: Nucleotide-diphospho-sugar transferases [53447] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest
  4. 2133076Superfamily c.68.1: Nucleotide-diphospho-sugar transferases [53448] (20 families) (S)
  5. 2133477Family c.68.1.9: alpha-1,3-galactosyltransferase-like [64131] (4 protein domains)
    automatically mapped to Pfam PF03414
  6. 2133522Protein Glycosyltransferase A catalytic domain [75276] (1 species)
    involved in blood group antigen biosynthesis
  7. 2133523Species Human (Homo sapiens) [TaxId:9606] [75277] (53 PDB entries)
    Uniprot P16442 64-345
  8. 2133546Domain d2a8wa2: 2a8w A:64-345 [126421]
    Other proteins in same PDB: d2a8wa3
    automated match to d1lz0a_
    complexed with cl, hg, mn, udp

Details for d2a8wa2

PDB Entry: 2a8w (more details), 1.59 Å

PDB Description: Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with Beta-Methyllactoside
PDB Compounds: (A:) Histo-blood group ABO system transferase (NAGAT) [Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase (EC (Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase) (Histo-blood group A transferase) (A transferase); Glycoprotein-fucosylgalactoside alpha- galactosyltransferase (EC (Fucosylglycoprotein 3-alpha- galactosyltransferase) (Histo-blood group B transferase) (B transferase)] [Contains: Fucosylglycoprotein alpha-N- acetylgalactosaminyltransferase, soluble form]

SCOPe Domain Sequences for d2a8wa2:

Sequence, based on SEQRES records: (download)

>d2a8wa2 c.68.1.9 (A:64-345) Glycosyltransferase A catalytic domain {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d2a8wa2 c.68.1.9 (A:64-345) Glycosyltransferase A catalytic domain {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2a8wa2:

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Timeline for d2a8wa2:

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