Lineage for d2a7qa_ (2a7q A:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2473887Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2473888Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2473889Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
    parallel beta-sheet of 5 strands, order 23145
  6. 2473984Protein Deoxycytidine kinase [89657] (1 species)
  7. 2473985Species Human (Homo sapiens) [TaxId:9606] [89658] (45 PDB entries)
  8. 2474052Domain d2a7qa_: 2a7q A: [126352]
    automated match to d1p5zb_
    complexed with adp, cfb, mg

Details for d2a7qa_

PDB Entry: 2a7q (more details), 2.55 Å

PDB Description: Crystal structure of human dCK complexed with clofarabine and ADP
PDB Compounds: (A:) Deoxycytidine kinase

SCOPe Domain Sequences for d2a7qa_:

Sequence, based on SEQRES records: (download)

>d2a7qa_ c.37.1.1 (A:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqstqdefeeltmsqkngg
nvlqmmyekperwsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifas
nlyesecmnetewtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqg
ipleyleklhykheswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflst
l

Sequence, based on observed residues (ATOM records): (download)

>d2a7qa_ c.37.1.1 (A:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqstnggnvlqmmyekper
wsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifasnlyesecmnete
wtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhyk
heswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflstl

SCOPe Domain Coordinates for d2a7qa_:

Click to download the PDB-style file with coordinates for d2a7qa_.
(The format of our PDB-style files is described here.)

Timeline for d2a7qa_: