Lineage for d2a7qa1 (2a7q A:20-260)

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 695085Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 695086Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families) (S)
    division into families based on beta-sheet topologies
  5. 695087Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (20 proteins)
    parallel beta-sheet of 5 strands, order 23145
  6. 695165Protein Deoxycytidine kinase [89657] (1 species)
  7. 695166Species Human (Homo sapiens) [TaxId:9606] [89658] (5 PDB entries)
  8. 695172Domain d2a7qa1: 2a7q A:20-260 [126352]
    automatically matched to d1p60a_
    complexed with adp, cfb, mg

Details for d2a7qa1

PDB Entry: 2a7q (more details), 2.55 Å

PDB Description: Crystal structure of human dCK complexed with clofarabine and ADP
PDB Compounds: (A:) Deoxycytidine kinase

SCOP Domain Sequences for d2a7qa1:

Sequence, based on SEQRES records: (download)

>d2a7qa1 c.37.1.1 (A:20-260) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqstqdefeeltmsqkngg
nvlqmmyekperwsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifas
nlyesecmnetewtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqg
ipleyleklhykheswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflst
l

Sequence, based on observed residues (ATOM records): (download)

>d2a7qa1 c.37.1.1 (A:20-260) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}
rikkisiegniaagkstfvnilkqlcedwevvpepvarwcnvqstnggnvlqmmyekper
wsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifasnlyesecmnete
wtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhyk
heswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflstl

SCOP Domain Coordinates for d2a7qa1:

Click to download the PDB-style file with coordinates for d2a7qa1.
(The format of our PDB-style files is described here.)

Timeline for d2a7qa1: