SCOPe 2.05: Domain d2a5ja1: 2a5j A:9-181

Lineage for d2a5ja1 (2a5j A:9-181)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rab2b [142287] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142288] (1 PDB entry)
   Uniprot Q8WUD1 4-176

8. Domain d2a5ja1: 2a5j A:9-181 [126175]
   complexed with gdp, mg

Details for d2a5ja1

PDB Entry: 2a5j, 1.5 Å

PDB Description: crystal structure of human rab2b

PDB Compounds: (A:) Ras-related protein Rab-2B

SCOPe Domain Sequences for d2a5ja1:

Sequence, based on SEQRES records:

>d2a5ja1 c.37.1.8 (A:9-181) Rab2b {Human (Homo sapiens) [TaxId: 9606]}
sylfkyiiigdtgvgksclllqftdkrfqpvhdltigvefgarmvnidgkqiklqiwdta
gqesfrsitrsyyrgaagallvyditrretfnhltswledarqhsssnmvimlignksdl
esrrdvkreegeafarehglifmetsaktacnveeafintakeiyrkiqqglf

Sequence, based on observed residues (ATOM records):

>d2a5ja1 c.37.1.8 (A:9-181) Rab2b {Human (Homo sapiens) [TaxId: 9606]}
sylfkyiiigdtgvgksclllqftdkrfqpigvefgarmvnidgkqiklqiwdtagqesf
rsitrsyyrgaagallvyditrretfnhltswledarqhsssnmvimlignksdlesrrd
vkreegeafarehglifmetsaktacnveeafintakeiyrkiqqglf

Timeline for d2a5ja1:

• d2a5ja1 first appeared in SCOP 1.73
  
• d2a5ja1 appears in SCOPe 2.04
  
• d2a5ja1 appears in SCOPe 2.06
  
• d2a5ja1 appears in the current release, SCOPe 2.08