Lineage for d1zxva1 (1zxv A:27-263)

  1. Root: SCOP 1.73
  2. 713694Class d: Alpha and beta proteins (a+b) [53931] (334 folds)
  3. 729090Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 729091Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (15 families) (S)
  5. 729579Family d.92.1.14: Anthrax toxin lethal factor, N- and C-terminal domains [69775] (1 protein)
  6. 729580Protein Anthrax toxin lethal factor, N- and C-terminal domains [69776] (1 species)
    duplication: each domain adopts a thermolysin-like fold, but the proteolytic activity resides only in the C-terminal domain
  7. 729581Species Bacillus anthracis [TaxId:1392] [69777] (9 PDB entries)
  8. 729587Domain d1zxva1: 1zxv A:27-263 [125797]
    Other proteins in same PDB: d1zxva3, d1zxvb3
    automatically matched to d1j7na1
    complexed with mfm, zn

Details for d1zxva1

PDB Entry: 1zxv (more details), 2.67 Å

PDB Description: X-Ray Crystal Structure of the Anthrax Lethal Factor Bound to a Small Molecule Inhibitor, BI-MFM3, 3-{5-[5-(4-Chloro-phenyl)-furan-2-ylmethylene]-4-oxo-2-thioxo-thiazolidin-3-yl}-propionic acid.
PDB Compounds: (A:) Lethal Factor

SCOP Domain Sequences for d1zxva1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1zxva1 d.92.1.14 (A:27-263) Anthrax toxin lethal factor, N- and C-terminal domains {Bacillus anthracis [TaxId: 1392]}

SCOP Domain Coordinates for d1zxva1:

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Timeline for d1zxva1: