SCOPe 2.06: Domain d1zx1b_: 1zx1 B:

Lineage for d1zx1b_ (1zx1 B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.23: Flavodoxin-like [52171] (15 superfamilies)
   3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345

4. Superfamily c.23.5: Flavoproteins [52218] (9 families)

5. Family c.23.5.3: Quinone reductase [52235] (4 proteins)
   binds FAD

6. Protein Quinone reductase type 2 (menadione reductase) [52240] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52241] (66 PDB entries)

8. Domain d1zx1b_: 1zx1 B: [125761]
   automated match to d1qr2a_
   complexed with cb1, fad, zn

Details for d1zx1b_

PDB Entry: 1zx1, 2.16 Å

PDB Description: human quinone oxidoreductase 2 (nqo2) in complex with the cytostatic prodrug cb1954

PDB Compounds: (B:) nrh dehydrogenase [quinone] 2

SCOPe Domain Sequences for d1zx1b_:

Sequence; same for both SEQRES and ATOM records:

>d1zx1b_ c.23.5.3 (B:) Quinone reductase type 2 (menadione reductase) {Human (Homo sapiens) [TaxId: 9606]}
gkkvlivyahqepksfngslknvavdelsrqgctvtvsdlyamnfepratdkditgtlsn
pevfnygvetheaykqrslasditdeqkkvreadlvifqfplywfsvpailkgwmdrvlc
qgfafdipgfydsgllqgklallsvttggtaemytktgvngdsryflwplqhgtlhfcgf
kvlapqisfapeiaseeerkgmvaawsqrlqtiwkeepipctahwhfgq

Timeline for d1zx1b_:

• d1zx1b_ first appeared in SCOP 1.73, called d1zx1b1
  
• d1zx1b_ appears in SCOPe 2.05
  
• d1zx1b_ appears in SCOPe 2.07
  
• d1zx1b_ appears in the current release, SCOPe 2.08