Lineage for d1zw9a2 (1zw9 A:4-214)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2537076Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
    8-stranded mixed beta-sheet; 2 layers: alpha/beta
  4. 2537077Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families) (S)
  5. 2537078Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)
  6. 2537079Protein HSP90 [55876] (3 species)
  7. 2537080Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55877] (32 PDB entries)
  8. 2537095Domain d1zw9a2: 1zw9 A:4-214 [125738]
    Other proteins in same PDB: d1zw9a3
    automated match to d2iwxa_
    complexed with h64

Details for d1zw9a2

PDB Entry: 1zw9 (more details), 1.9 Å

PDB Description: Yeast HSP82 in complex with the Novel HSP90 Inhibitor 8-(6-Bromo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)-adenine
PDB Compounds: (A:) hsp82

SCOPe Domain Sequences for d1zw9a2:

Sequence, based on SEQRES records: (download)

>d1zw9a2 d.122.1.1 (A:4-214) HSP90 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
etfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletepdlf
iritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqfgvg
fyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddqle
yleekrikevikrhsefvaypiqlvvtkeve

Sequence, based on observed residues (ATOM records): (download)

>d1zw9a2 d.122.1.1 (A:4-214) HSP90 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
etfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletepdlf
iritpkpeqkvleirdsgigmtkaelinsgtkafmealsagadvsmigqfgvgfyslflv
adrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddqleyleekri
kevikrhsefvaypiqlvvtkeve

SCOPe Domain Coordinates for d1zw9a2:

Click to download the PDB-style file with coordinates for d1zw9a2.
(The format of our PDB-style files is described here.)

Timeline for d1zw9a2:

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Domains from same chain:
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d1zw9a3