SCOPe 2.08: Domain d1zw9a2: 1zw9 A:4-214

Lineage for d1zw9a2 (1zw9 A:4-214)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)

6. Protein HSP90 [55876] (3 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55877] (32 PDB entries)

8. Domain d1zw9a2: 1zw9 A:4-214 [125738]
   Other proteins in same PDB: d1zw9a3
   automated match to d2iwxa_
   complexed with h64

Details for d1zw9a2

PDB Entry: 1zw9, 1.9 Å

PDB Description: Yeast HSP82 in complex with the Novel HSP90 Inhibitor 8-(6-Bromo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)-adenine

PDB Compounds: (A:) hsp82

SCOPe Domain Sequences for d1zw9a2:

Sequence, based on SEQRES records:

>d1zw9a2 d.122.1.1 (A:4-214) HSP90 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
etfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletepdlf
iritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqfgvg
fyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddqle
yleekrikevikrhsefvaypiqlvvtkeve

Sequence, based on observed residues (ATOM records):

>d1zw9a2 d.122.1.1 (A:4-214) HSP90 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
etfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletepdlf
iritpkpeqkvleirdsgigmtkaelinsgtkafmealsagadvsmigqfgvgfyslflv
adrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddqleyleekri
kevikrhsefvaypiqlvvtkeve

Timeline for d1zw9a2:

• d1zw9a2 first appeared in SCOP 1.73, called d1zw9a1
  
• d1zw9a2 appears in SCOPe 2.07