Lineage for d1zvob1 (1zvo B:3-108)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2019185Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 2019263Species Human (Homo sapiens), cluster 5 [TaxId:9606] [88540] (7 PDB entries)
    Uniprot Q8N355 20-230 # 94% sequence identity; natural chimera: antibody light chain (Fab HYB3)
  8. 2019275Domain d1zvob1: 1zvo B:3-108 [125712]
    Other proteins in same PDB: d1zvoa2, d1zvob2
    automatically matched to d1adql1

Details for d1zvob1

PDB Entry: 1zvo (more details)

PDB Description: Semi-extended solution structure of human myeloma immunoglobulin D determined by constrained X-ray scattering
PDB Compounds: (B:) myeloma immunoglobulin D lambda

SCOPe Domain Sequences for d1zvob1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1zvob1 b.1.1.1 (B:3-108) Immunoglobulin light chain lambda variable domain, VL-lambda {Human (Homo sapiens), cluster 5 [TaxId: 9606]}
vltqppsasgtpgqrvtiscfgsssnigryyvywyqqlpgttpklliykdnqrpsgvpdr
fsgsksgtsaslaisglrsedeadyycaawddslwvfgggttltvl

SCOPe Domain Coordinates for d1zvob1:

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Timeline for d1zvob1:

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Domains from same chain:
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d1zvob2