Lineage for d1zsna_ (1zsn A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2090553Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2091104Protein Enoyl-ACP reductase [51791] (11 species)
  7. 2091172Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [82296] (23 PDB entries)
    Uniprot Q9BJJ9 96-424 # fragment
  8. 2091212Domain d1zsna_: 1zsn A: [125608]
    automated match to d1uh5a_
    complexed with nad, tn2

Details for d1zsna_

PDB Entry: 1zsn (more details), 2.99 Å

PDB Description: synthesis, biological activity, and x-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acp reductase. part 1:4'-substituted triclosan derivatives
PDB Compounds: (A:) enoyl-acyl carrier reductase

SCOPe Domain Sequences for d1zsna_:

Sequence, based on SEQRES records: (download)

>d1zsna_ c.2.1.2 (A:) Enoyl-ACP reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
edicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkd
kkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsl
anakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpg
ygggmssakaalesdtrvlayhlgrnynirintisagplksraatainklnntyenntnq
nknrnshdvhnimnnsgekeekknsasqnytfidyaieysekyaplrqkllstdigsvas
fllsresraitgqtiyvdnglnimflpddiyrn

Sequence, based on observed residues (ATOM records): (download)

>d1zsna_ c.2.1.2 (A:) Enoyl-ACP reductase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
edicfiagigdtngygwgiakelskrnvkiifgiwppvynifmknykngkfdndmiidkd
kkmnildmlpfdasfdtandideetknnkrynmlqnytiedvanlihqkygkinmlvhsl
anakevqkdllntsrkgyldalskssyslislckyfvnimkpqssiisltyhasqkvvpg
ygggmssakaalesdtrvlayhlgrnynirintisagplksraatainytfidyaieyse
kyaplrqkllstdigsvasfllsresraitgqtiyvdnglnimflpddiyrn

SCOPe Domain Coordinates for d1zsna_:

Click to download the PDB-style file with coordinates for d1zsna_.
(The format of our PDB-style files is described here.)

Timeline for d1zsna_: