SCOPe 2.08: Domain d1zr5a1: 1zr5 A:179-367

Lineage for d1zr5a1 (1zr5 A:179-367)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.50: Macro domain-like [52948] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 6 strands, order 165243, strand 3 is antiparallel to the rest

4. Superfamily c.50.1: Macro domain-like [52949] (4 families)

5. Family c.50.1.2: Macro domain [89724] (7 proteins)
   found in different proteins, including macro-H2a histone and the Appr-1"-p processing enzyme

6. Protein Histone macro-H2a1.1 [142547] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142549] (6 PDB entries)
   Uniprot O75367 179-367! Uniprot O75367 181-371

8. Domain d1zr5a1: 1zr5 A:179-367 [125525]

Details for d1zr5a1

PDB Entry: 1zr5, 2.92 Å

PDB Description: Crystal structure of the macro-domain of human core histone variant macroH2A1.2

PDB Compounds: (A:) H2AFY protein

SCOPe Domain Sequences for d1zr5a1:

Sequence; same for both SEQRES and ATOM records:

>d1zr5a1 c.50.1.2 (A:179-367) Histone macro-H2a1.1 {Human (Homo sapiens) [TaxId: 9606]}
dgftvlstkslflgqklnlihseisnlagfeveaiinptnadidlkddlgntlekkggke
fveavlelrkkngplevagaavsaghglpakfvihcnspvwgadkceellektvknclal
addkklksiafpsigsgrngfpkqtaaqlilkaissyfvstmsssiktvyfvlfdsesig
iyvqemakl

Timeline for d1zr5a1:

• d1zr5a1 first appeared in SCOP 1.73
  
• d1zr5a1 appears in SCOPe 2.07