SCOP 1.73: Domain d1zpka1: 1zpk A:1-99

Lineage for d1zpka1 (1zpk A:1-99)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (2 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (8 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (1 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (230 PDB entries)

8. Domain d1zpka1: 1zpk A:1-99 [125465]
   automatically matched to d1lzqa_
   complexed with boc, cl, na, nh2, pr0; mutant

Details for d1zpka1

PDB Entry: 1zpk, 1.65 Å

PDB Description: crystal structure of the complex of mutant hiv-1 protease (a71v, v82t, i84v) with a hydroxyethylamine peptidomimetic inhibitor boc-phe- psi[r-ch(oh)ch2nh]-phe-glu-phe-nh2

PDB Compounds: (A:) protease retropepsin

SCOP Domain Sequences for d1zpka1:

Sequence; same for both SEQRES and ATOM records:

>d1zpka1 b.50.1.1 (A:1-99) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkvigtvlvgptptnvigrnlltqigctlnf

Timeline for d1zpka1:

• d1zpka1 is new in SCOP 1.73
  
• d1zpka1 appears in SCOP 1.75
  
• d1zpka1 appears in the current release, SCOPe 2.08, called d1zpka_