SCOP 1.75: Domain d1zkna1: 1zkn A:79-412

Lineage for d1zkna1 (1zkn A:79-412)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (5 families)

5. Family a.211.1.2: PDEase [48548] (6 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein Catalytic domain of cyclic nucleotide phosphodiesterase pde4d [89151] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89152] (22 PDB entries)
   Uniprot Q08499 388-713

8. Domain d1zkna1: 1zkn A:79-412 [125201]
   automatically matched to d1oyna_
   complexed with ibm, mg, zn

Details for d1zkna1

PDB Entry: 1zkn, 2.1 Å

PDB Description: Structure of PDE4D2-IBMX

PDB Compounds: (A:) cAMP-specific 3',5'-cyclic phosphodiesterase 4D

SCOP Domain Sequences for d1zkna1:

Sequence; same for both SEQRES and ATOM records:

>d1zkna1 a.211.1.2 (A:79-412) Catalytic domain of cyclic nucleotide phosphodiesterase pde4d {Human (Homo sapiens) [TaxId: 9606]}
iprfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkip
vdtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasa
ihdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrq
slrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcad
lsnptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivh
plwetwadlvhpdaqdildtlednrewyqstipq

Timeline for d1zkna1:

• d1zkna1 first appeared in SCOP 1.73
  
• d1zkna1 is called d1zkna_ in SCOPe 2.01
  
• d1zkna1 appears in the current release, SCOPe 2.08, called d1zkna_