SCOPe 2.04: Domain d1ziva1: 1ziv A:28-337

Lineage for d1ziva1 (1ziv A:28-337)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (23 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.3: Calpain large subunit, catalytic domain (domain II) [54040] (1 protein)
   automatically mapped to Pfam PF00648

6. Protein Calpain large subunit, catalytic domain (domain II) [54041] (6 species)
   includes the N-terminal 'sequence' domain I

7. Species Human (Homo sapiens), calpain 9 [TaxId:9606] [142850] (1 PDB entry)
   Uniprot O14815 28-337

8. Domain d1ziva1: 1ziv A:28-337 [125139]
   complexed with bme, ca

Details for d1ziva1

PDB Entry: 1ziv, 2.31 Å

PDB Description: Catalytic Domain of Human Calpain-9

PDB Compounds: (A:) Calpain 9

SCOPe Domain Sequences for d1ziva1:

Sequence, based on SEQRES records:

>d1ziva1 d.3.1.3 (A:28-337) Calpain large subunit, catalytic domain (domain II) {Human (Homo sapiens), calpain 9 [TaxId: 9606]}
sfeqmrqeclqrgtlfedadfpasnsslfyserpqipfvwkrpgeivknpefilggatrt
dicqgelgdcwllaaiasltlnqkalarvipqdqsfgpgyagifhfqfwqhsewldvvid
drlptfrdrlvflhsadhnefwsallekayaklngsyealkggsaieamedftggvaetf
qtkeapenfyeilekalkrgsllgcfidtrsaaeseartpfglikghaysvtgidqvsfr
gqrielirirnpwgqvewngswsdsspewrsvgpaeqkrlchtalddgefwmafkdfkah
fdkveicnlt

Sequence, based on observed residues (ATOM records):

>d1ziva1 d.3.1.3 (A:28-337) Calpain large subunit, catalytic domain (domain II) {Human (Homo sapiens), calpain 9 [TaxId: 9606]}
sfeqmrqeclqrgtlfedadfpasnsslfyspqipfvwkrpgeivknpefilggatrtdi
cqgelgdcwllaaiasltlnqkalarvipqdqsfgpgyagifhfqfwqhsewldvviddr
lptfrdrlvflhsadhnefwsallekayaklngsyealkggsaieamedftggvaetfqt
keapenfyeilekalkrgsllgcfidtrsaaeseartpfglikghaysvtgidqvsfrgq
rielirirnpwgqvewngswsdsspewrsvgpaeqkrlchtalddgefwmafkdfkahfd
kveicnlt

Timeline for d1ziva1:

• d1ziva1 first appeared in SCOP 1.73
  
• d1ziva1 appears in SCOPe 2.03
  
• d1ziva1 appears in SCOPe 2.05
  
• d1ziva1 appears in the current release, SCOPe 2.08