SCOPe 2.08: Domain d1zi5a2: 1zi5 A:64-345

Lineage for d1zi5a2 (1zi5 A:64-345)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.68: Nucleotide-diphospho-sugar transferases [53447] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest

4. Superfamily c.68.1: Nucleotide-diphospho-sugar transferases [53448] (20 families)

5. Family c.68.1.9: alpha-1,3-galactosyltransferase-like [64131] (4 proteins)
   automatically mapped to Pfam PF03414

6. Protein Glycosyltransferase A catalytic domain [75276] (1 species)
   involved in blood group antigen biosynthesis

7. Species Human (Homo sapiens) [TaxId:9606] [75277] (59 PDB entries)
   Uniprot P16442 64-345

8. Domain d1zi5a2: 1zi5 A:64-345 [125118]
   Other proteins in same PDB: d1zi5a3
   automated match to d1lz0a_
   complexed with hg, udp

Details for d1zi5a2

PDB Entry: 1zi5, 1.55 Å

PDB Description: crystal structure of human n-acetylgalactosaminyltransferase (gta) complexed with h type i trisaccharide

PDB Compounds: (A:) Histo-blood group ABO system transferase (NAGAT) Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase

SCOPe Domain Sequences for d1zi5a2:

Sequence, based on SEQRES records:

>d1zi5a2 c.68.1.9 (A:64-345) Glycosyltransferase A catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
vslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvfai
kkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevraykrwqd
vsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpgfygssrea
ftyerrpqsqayipkdegdfyylggffggsvqevqrltrachqammvdqangieavwhde
shlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavp

Sequence, based on observed residues (ATOM records):

>d1zi5a2 c.68.1.9 (A:64-345) Glycosyltransferase A catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
vslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvfai
kkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevrerrflse
vdylvcvdvdmefrdhvgveiltplfgtlhpgfygssreaftyerrpqsqayipkdegdf
yylggffggsvqevqrltrachqammvdqangieavwhdeshlnkyllrhkptkvlspey
lwdqqllgwpavlrklrftavp

Timeline for d1zi5a2:

• d1zi5a2 first appeared in SCOP 1.73, called d1zi5a1
  
• d1zi5a2 appears in SCOPe 2.07