SCOP 1.73: Domain d1zgia1: 1zgi A:1A-245

Lineage for d1zgia1 (1zgi A:1A-245)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (163 PDB entries)

8. Domain d1zgia1: 1zgi A:1A-245 [125030]
   automatically matched to d1jwta_
   complexed with 382

Details for d1zgia1

PDB Entry: 1zgi, 2.2 Å

PDB Description: thrombin in complex with an oxazolopyridine inhibitor 21

PDB Compounds: (A:) thrombin

SCOP Domain Sequences for d1zgia1:

Sequence, based on SEQRES records:

>d1zgia1 b.47.1.2 (A:1A-245) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
dcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcgas
lisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpryn
wrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtan
vgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvm
kspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqf

Sequence, based on observed residues (ATOM records):

>d1zgia1 b.47.1.2 (A:1A-245) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
dcglrplfekksledkterellesyiivegsdaeigmspwqvmlfrkspqellcgaslis
drwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynwre
nldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlkegqpsvlqv
vnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqm
givswgegcdrdgkygfythvfrlkkwiqkvidqf

Timeline for d1zgia1:

• d1zgia1 is new in SCOP 1.73
  
• d1zgia1 appears in SCOP 1.75
  
• d1zgia1 appears in the current release, SCOPe 2.08, called d1zgia_