SCOPe 2.06: Domain d1zeoa_: 1zeo A:

Lineage for d1zeoa_ (1zeo A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (113 PDB entries)
   Uniprot P37231 232-505

8. Domain d1zeoa_: 1zeo A: [124992]
   automated match to d1wm0x_
   complexed with c01

Details for d1zeoa_

PDB Entry: 1zeo, 2.5 Å

PDB Description: crystal structure of human ppar-gamma ligand binding domain complexed with an alpha-aryloxyphenylacetic acid agonist

PDB Compounds: (A:) Peroxisome proliferator activated receptor gamma

SCOPe Domain Sequences for d1zeoa_:

Sequence, based on SEQRES records:

>d1zeoa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d1zeoa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikeqs
kevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslm
nkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviils
gdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllq
vikktetdmslhpllqeiykdly

Timeline for d1zeoa_:

• d1zeoa_ first appeared in SCOP 1.73, called d1zeoa1
  
• d1zeoa_ appears in SCOPe 2.05
  
• d1zeoa_ appears in SCOPe 2.07
  
• d1zeoa_ appears in the current release, SCOPe 2.08