SCOP 1.75: Domain d1zeoa1: 1zeo A:207-477

Lineage for d1zeoa1 (1zeo A:207-477)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (46 PDB entries)
   Uniprot P37231 232-505

8. Domain d1zeoa1: 1zeo A:207-477 [124992]
   automatically matched to d1wm0x_
   complexed with c01

Details for d1zeoa1

PDB Entry: 1zeo, 2.5 Å

PDB Description: crystal structure of human ppar-gamma ligand binding domain complexed with an alpha-aryloxyphenylacetic acid agonist

PDB Compounds: (A:) Peroxisome proliferator activated receptor gamma

SCOP Domain Sequences for d1zeoa1:

Sequence, based on SEQRES records:

>d1zeoa1 a.123.1.1 (A:207-477) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d1zeoa1 a.123.1.1 (A:207-477) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikeqs
kevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslm
nkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviils
gdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllq
vikktetdmslhpllqeiykdly

Timeline for d1zeoa1:

• d1zeoa1 first appeared in SCOP 1.73
  
• d1zeoa1 is called d1zeoa_ in SCOPe 2.01
  
• d1zeoa1 appears in the current release, SCOPe 2.08, called d1zeoa_