Lineage for d1z8aa_ (1z8a A:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2434695Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2437818Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 2437819Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 proteins)
    Common fold covers whole protein structure
  6. 2438218Protein automated matches [190169] (7 species)
    not a true protein
  7. 2438223Species Human (Homo sapiens) [TaxId:9606] [188399] (47 PDB entries)
  8. 2438231Domain d1z8aa_: 1z8a A: [124696]
    automated match to d1pwla_
    complexed with 62p, nap

Details for d1z8aa_

PDB Entry: 1z8a (more details), 0.95 Å

PDB Description: human aldose reductase complexed with novel sulfonyl-pyridazinone inhibitor
PDB Compounds: (A:) aldose reductase

SCOPe Domain Sequences for d1z8aa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1z8aa_ c.1.7.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1z8aa_:

Click to download the PDB-style file with coordinates for d1z8aa_.
(The format of our PDB-style files is described here.)

Timeline for d1z8aa_: