Lineage for d1z6ea1 (1z6e A:16-244)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 670182Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 670183Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families) (S)
  5. 670328Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)
  6. 670527Protein Coagulation factor Xa, protease domain [50574] (2 species)
  7. 670530Species Human (Homo sapiens) [TaxId:9606] [50575] (58 PDB entries)
  8. 670535Domain d1z6ea1: 1z6e A:16-244 [124518]
    Other proteins in same PDB: d1z6eb1
    automatically matched to d1c5md_
    complexed with ik8

Details for d1z6ea1

PDB Entry: 1z6e (more details), 1.8 Å

PDB Description: Factor XA in complex with the inhibitor 1-(3'-amino-1,2-benzisoxazol-5'-yl)-n-(4-(2'-((dimethylamino)methyl)-1h-imidazol-1-yl)-2-fluorophenyl)-3-(trifluoromethyl)-1h-pyrazole-5-carboxamide (razaxaban; DPC906; BMS-561389)
PDB Compounds: (A:) coagulation factor x

SCOP Domain Sequences for d1z6ea1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1z6ea1 b.47.1.2 (A:16-244) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

SCOP Domain Coordinates for d1z6ea1:

Click to download the PDB-style file with coordinates for d1z6ea1.
(The format of our PDB-style files is described here.)

Timeline for d1z6ea1: