SCOPe 2.08: Domain d1z2cb1: 1z2c B:83-443

Lineage for d1z2cb1 (1z2c B:83-443)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (28 families)

5. Family a.118.1.23: Diap1 N-terninal region-like [140830] (2 proteins)
   contains two consequitive Pfam domains in one superhelical segment: Pfam PF06371 and Pfam PF06367
   this is a repeat family; one repeat unit is 2bap A:217-262 found in domain

6. Protein Diaphanous protein homolog 1, Diap1 (Dia1, DRF1) [140831] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [140832] (4 PDB entries)
   Uniprot O08808 133-475! Uniprot O08808 135-435! Uniprot O08808 83-443

8. Domain d1z2cb1: 1z2c B:83-443 [124377]
   Other proteins in same PDB: d1z2ca1, d1z2cc_
   complexed with gnp, mg

Details for d1z2cb1

PDB Entry: 1z2c, 3 Å

PDB Description: crystal structure of mdia1 gbd-fh3 in complex with rhoc-gmppnp

PDB Compounds: (B:) Diaphanous protein homolog 1

SCOPe Domain Sequences for d1z2cb1:

Sequence, based on SEQRES records:

>d1z2cb1 a.118.1.23 (B:83-443) Diaphanous protein homolog 1, Diap1 (Dia1, DRF1) {Mouse (Mus musculus) [TaxId: 10090]}
vlvlfeqmlvdmnlneekqqplrekdivikremvsqylhtskagmnqkessrsammyiqe
lrsglrdmhllscleslrvslnnnpvswvqtfgaeglaslldilkrlhdekeetsgnyds
rnqheiirclkafmnnkfgiktmleteegilllvramdpavpnmmidaakllsalcilpq
pedmnervleamteraemdeverfqplldglksgtsialkvgclqlinalitpaeeldfr
vhirselmrlglhqvlqelreienedmkvqlcvfdeqgdedffdlkgrlddirmemddfg
evfqiilntvkdskaephflsilqhlllvrndyearpqyyklieecvsqivlhkngtdpd
f

Sequence, based on observed residues (ATOM records):

>d1z2cb1 a.118.1.23 (B:83-443) Diaphanous protein homolog 1, Diap1 (Dia1, DRF1) {Mouse (Mus musculus) [TaxId: 10090]}
vlvlfeqmlvdmnlneekqqplrekdivikremvsqylhtsssrsammyiqelrsglrdm
hllscleslrvslnnnpvswvqtfgaeglaslldilkrlhdekdsrnqheiirclkafmn
nkfgiktmleteegilllvramdpavpnmmidaakllsalcilpqpedmnervleamter
aemdeverfqplldglksgtsialkvgclqlinalitpaeeldfrvhirselmrlglhqv
lqelreienedmkvqlcvfdeqgdedffdlkgrlddirmemddfgevfqiilntvkdska
ephflsilqhlllvrndyearpqyyklieecvsqivlhkngtdpdf

Timeline for d1z2cb1:

• d1z2cb1 first appeared in SCOP 1.73
  
• d1z2cb1 appears in SCOPe 2.07