SCOPe 2.02: Domain d1z25a2: 1z25 A:324-770

Lineage for d1z25a2 (1z25 A:324-770)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (15 families)
   consists of one domain of this fold

5. Family c.55.3.10: PIWI domain [110640] (3 proteins)
   Pfam PF02171

6. Protein Argonaute homologue PF0537 [110641] (1 species)
   includes the middle domain

7. Species Pyrococcus furiosus [TaxId:2261] [110642] (3 PDB entries)
   Uniprot Q8U3D2

8. Domain d1z25a2: 1z25 A:324-770 [124371]
   Other proteins in same PDB: d1z25a1
   automatically matched to d1u04a2
   complexed with mn

Details for d1z25a2

PDB Entry: 1z25, 2.7 Å

PDB Description: structure of p.furiosus argonaute with bound mn2+

PDB Compounds: (A:) Argonaute

SCOPe Domain Sequences for d1z25a2:

Sequence, based on SEQRES records:

>d1z25a2 c.55.3.10 (A:324-770) Argonaute homologue PF0537 {Pyrococcus furiosus [TaxId: 2261]}
iaqelenkirvrddkgnsvpisqlnvqksqlllwtnysrkypvilpyevpekfrkireip
mfiildsglladiqnfatnefrelvksmyyslakkynslakkarstneiglpfldfrgke
kvitedlnsdkgiievveqvssfmkgkelglafiaarnklssekfeeikrrlfnlnvisq
vvnedtlknkrdkydrnrldlfvrhnllfqvlsklgvkyyvldyrfnydyiigidvapmk
rsegyiggsavmfdsqgyirkivpikigeqrgesvdmneffkemvdkfkefnikldnkki
lllrdgritnneeeglkyisemfdievvtmdviknhpvrafanmkmyfnlggaiyliphk
lkqakgtpipiklakkriikngkvekqsitrqdvldifiltrlnygsisadmrlpapvhy
ahkfanairnewkikeeflaegflyfv

Sequence, based on observed residues (ATOM records):

>d1z25a2 c.55.3.10 (A:324-770) Argonaute homologue PF0537 {Pyrococcus furiosus [TaxId: 2261]}
iaqelenkirvrddkgnsvpisqllwtnysrkypvilpyevpekfrkireipmfiildsg
lladiqnfatnefrelvksmyyekvitedlnsdkgiievveqvssfmkgkelglafiaar
nklssekfeeikrrlfnlnvisqvvnedtlknkrdkydrnrldlfvrhnllfqvlsklgv
kyyvldyrfnydyiigidvapmkrsegyiggsavmfdsqgyirkivpikigeqrgesvdm
neffkemvdkfkefnikldnkkilllrdgritnneeeglkyisemfdievvtmdviknhp
vrafanmkmyfnlggaiyliphklkqakgtpipiklakkriikngkvekqsitrqdvldi
filtrlnygsisadmrlpapvhyahkfanairnewkikeeflaegflyfv

Timeline for d1z25a2:

• d1z25a2 first appeared in SCOP 1.73
  
• d1z25a2 appears in SCOPe 2.01
  
• d1z25a2 appears in SCOPe 2.03
  
• d1z25a2 last appears in SCOPe 2.05