SCOPe 2.08: Domain d1yyna2: 1yyn A:1111-1315

Lineage for d1yyna2 (1yyn A:1111-1315)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.4: STI-like [50386] (3 families)

5. Family b.42.4.2: Clostridium neurotoxins, C-terminal domain [50399] (3 proteins)
   overall fold is very similar to that of the STI family
   automatically mapped to Pfam PF07951

6. Protein Tetanus neurotoxin [50400] (1 species)

7. Species Clostridium tetani [TaxId:1513] [50401] (10 PDB entries)

8. Domain d1yyna2: 1yyn A:1111-1315 [124243]
   Other proteins in same PDB: d1yyna1
   automated match to d1dlla2

Details for d1yyna2

PDB Entry: 1yyn, 2.3 Å

PDB Description: a common binding site for disialyllactose and a tri-peptide in the c- fragment of tetanus neurotoxin

PDB Compounds: (A:) Tetanus toxin

SCOPe Domain Sequences for d1yyna2:

Sequence; same for both SEQRES and ATOM records:

>d1yyna2 b.42.4.2 (A:1111-1315) Tetanus neurotoxin {Clostridium tetani [TaxId: 1513]}
itflrdfwgnplrydteyylipvassskdvqlknitdymyltnapsytngklniyyrrly
nglkfiikrytpnneidsfvksgdfiklyvsynnnehivgypkdgnafnnldrilrvgyn
apgiplykkmeavklrdlktysvqlklyddknaslglvgthngqigndpnrdiliasnwy
fnhlkdkilgcdwyfvptdegwtnd

Timeline for d1yyna2:

• d1yyna2 first appeared in SCOP 1.73
  
• d1yyna2 appears in SCOPe 2.07