SCOPe 2.08: Domain d1yt7a_: 1yt7 A:

Lineage for d1yt7a_ (1yt7 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein (Pro)cathepsin K [54028] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [54029] (56 PDB entries)
   Uniprot P43235 116-329 ! Uniprot P43235 115-329

8. Domain d1yt7a_: 1yt7 A: [123995]
   automated match to d2r6na1
   complexed with 3fc, so4

Details for d1yt7a_

PDB Entry: 1yt7, 2.3 Å

PDB Description: Cathepsin K complexed with a constrained ketoamide inhibitor

PDB Compounds: (A:) cathepsin k

SCOPe Domain Sequences for d1yt7a_:

Sequence; same for both SEQRES and ATOM records:

>d1yt7a_ d.3.1.1 (A:) (Pro)cathepsin K {Human (Homo sapiens) [TaxId: 9606]}
pdsvdyrkkgyvtpvknqgqcgscwafssvgalegqlkkktgkllnlspqnlvdcvsend
gcgggymtnafqyvqknrgidsedaypyvgqeescmynptgkaakcrgyreipegnekal
kravarvgpvsvaidasltsfqfyskgvyydescnsdnlnhavlavgygiqkgnkhwiik
nswgenwgnkgyilmarnknnacgianlasfpkm

Timeline for d1yt7a_:

• d1yt7a_ first appeared in SCOP 1.73, called d1yt7a1
  
• d1yt7a_ appears in SCOPe 2.07