SCOP 1.73: Domain d1ysza1: 1ysz A:74-337

Lineage for d1ysza1 (1ysz A:74-337)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (4 families)

5. Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (1 protein)

6. Protein HSP90 [55876] (3 species)

7. Species Dog (Canis familiaris) [TaxId:9615] [103225] (20 PDB entries)

8. Domain d1ysza1: 1ysz A:74-337 [123987]
   automatically matched to d1u2oa_
   complexed with nec, pg4; mutant

Details for d1ysza1

PDB Entry: 1ysz, 2.65 Å

PDB Description: crystal structure of the unliganded form of grp94, the er hsp90: basis for nucleotide-induced conformational change, grp94n(delta)41 apo crystal soaked with neca

PDB Compounds: (A:) Endoplasmin

SCOP Domain Sequences for d1ysza1:

Sequence, based on SEQRES records:

>d1ysza1 d.122.1.1 (A:74-337) HSP90 {Dog (Canis familiaris) [TaxId: 9615]}
ekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneelt
vkikcdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqedgqstselig
qfgvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlke
easdyleldtiknlvkkysqfinfpiyvwssktggggktvwdwelmn

Sequence, based on observed residues (ATOM records):

>d1ysza1 d.122.1.1 (A:74-337) HSP90 {Dog (Canis familiaris) [TaxId: 9615]}
ekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneelt
vkikcdkeknllhvtdtgvgmtreelvknlgtigtseflnkmteaqestseligqfgvgf
ysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlkeeasdyl
eldtiknlvkkysqfinfpiyvwssktktvwdwelmn

Timeline for d1ysza1:

• d1ysza1 is new in SCOP 1.73
  
• d1ysza1 appears in SCOP 1.75
  
• d1ysza1 appears in the current release, SCOPe 2.08, called d1ysza_