Lineage for d1ysna2 (1ysn A:5-213)

  1. Root: SCOPe 2.08
  2. 3021034Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)
  3. 3021035Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 3021129Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 3021130Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
    Pfam PF00452
  6. 3021136Protein Apoptosis regulator Bcl-xL [56856] (3 species)
  7. 3021137Species Human (Homo sapiens) [TaxId:9606] [56857] (51 PDB entries)
  8. 3021234Domain d1ysna2: 1ysn A:5-213 [123980]
    Other proteins in same PDB: d1ysna3, d1ysna4
    automated match to d1g5ja_
    complexed with 43b

    has additional insertions and/or extensions that are not grouped together

Details for d1ysna2

PDB Entry: 1ysn (more details)

PDB Description: solution structure of the anti-apoptotic protein bcl-xl complexed with an acyl-sulfonamide-based ligand
PDB Compounds: (A:) apoptosis regulator bcl-x

SCOPe Domain Sequences for d1ysna2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ysna2 f.1.4.1 (A:5-213) Apoptosis regulator Bcl-xL {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1ysna2:

Click to download the PDB-style file with coordinates for d1ysna2.
(The format of our PDB-style files is described here.)

Timeline for d1ysna2: