Lineage for d1ym2c_ (1ym2 C:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2799129Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2799130Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2800798Family b.50.1.2: Pepsin-like [50646] (11 proteins)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 2802193Protein automated matches [190156] (5 species)
    not a true protein
  7. 2802388Species Human (Homo sapiens) [TaxId:9606] [187237] (38 PDB entries)
  8. 2802397Domain d1ym2c_: 1ym2 C: [123681]
    automated match to d1fkna_

Details for d1ym2c_

PDB Entry: 1ym2 (more details), 2.05 Å

PDB Description: Crystal structure of human beta secretase complexed with NVP-AUR200
PDB Compounds: (C:) Beta-secretase 1

SCOPe Domain Sequences for d1ym2c_:

Sequence, based on SEQRES records: (download)

>d1ym2c_ b.50.1.2 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sfvemvdnlrgksgqgyyvemtvgsppqtlnilvdtgssnfavgaaphpflhryyqrqls
styrdlrkgvyvpytqgkwegelgtdlvsiphgpnvtvraniaaitesdkffingsnweg
ilglayaeiarpddslepffdslvkqthvpnlfslqlcgagfplnqsevlasvggsmiig
gidhslytgslwytpirrewyyeviivrveingqdlkmdckeynydksivdsgttnlrlp
kkvfeaavksikaasstekfpdgfwlgeqlvcwqagttpwnifpvislylmgevtnqsfr
itilpqqylrpvedvatsqddcykfaisqsstgtvmgavimegfyvvfdrarkrigfavs
achvhdefrtaavegpfvtldmedcgyn

Sequence, based on observed residues (ATOM records): (download)

>d1ym2c_ b.50.1.2 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sfvemvdnlrgksgqgyyvemtvgsppqtlnilvdtgssnfavgaaphpflhryyqrqls
styrdlrkgvyvpytqgkwegelgtdlvsiphgpnvtvraniaaitesdkffingsnweg
ilglayaeiarpddslepffdslvkqthvpnlfslqlcgavggsmiiggidhslytgslw
ytpirrewyyeviivrveingqdlkmdckeynydksivdsgttnlrlpkkvfeaavksik
aasstekfpdgfwlgeqlvcwqagttpwnifpvislylmgevtnqsfritilpqqylrpv
edvatsqddcykfaisqsstgtvmgavimegfyvvfdrarkrigfavsachvhdefrtaa
vegpfvtldmedcgyn

SCOPe Domain Coordinates for d1ym2c_:

Click to download the PDB-style file with coordinates for d1ym2c_.
(The format of our PDB-style files is described here.)

Timeline for d1ym2c_: