SCOPe 2.06: Domain d1yksa2: 1yks A:325-623

Lineage for d1yksa2 (1yks A:325-623)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.14: RNA helicase [52724] (4 proteins)
   duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension

6. Protein YFV helicase domain [142330] (1 species)

7. Species Yellow fever virus [TaxId:11089] [142331] (2 PDB entries)
   Uniprot P19901 1669-1842! Uniprot P19901 1843-2107

8. Domain d1yksa2: 1yks A:325-623 [123562]
   Other proteins in same PDB: d1yksa3

Details for d1yksa2

PDB Entry: 1yks, 1.8 Å

PDB Description: Crystal structure of yellow fever virus NS3 helicase

PDB Compounds: (A:) Genome polyprotein [contains: Flavivirin protease NS3 catalytic subunit]

SCOPe Domain Sequences for d1yksa2:

Sequence, based on SEQRES records:

>d1yksa2 c.37.1.14 (A:325-623) YFV helicase domain {Yellow fever virus [TaxId: 11089]}
gtsdefphsngeiedvqtdipsepwntghdwiladkrptawflpsiraanvmaaslrkag
ksvvvlnrktfereyptikqkkpdfilatdiaemganlcvervldcrtafkpvlvdegrk
vaikgplrisassaaqrrgrigrnpnrdgdsyyyseptsennahhvcwleasmlldnmev
rggmvaplygvegtktpvspgemrlrddqrkvfrelvrncdlpvwlswqvakaglktndr
kwcfegpeeheilndsgetvkcrapggakkplrprwcdervssdqsalsefikfaegrr

Sequence, based on observed residues (ATOM records):

>d1yksa2 c.37.1.14 (A:325-623) YFV helicase domain {Yellow fever virus [TaxId: 11089]}
gtsdefphsngeiedvqtdipsepwntghdwiladkrptawflpsiraanvmaaslrkag
ksvvvlnrktfekkpdfilatdiaemganlcvervldcrtafkpvlvdegrkvaikgplr
isassaaqrrgrigrnpnrdgdsyyyseptsennahhvcwleasmlldnmevrggmvapl
ygvegtktpvspgemrlrddqrkvfrelvrncdlpvwlswqvakaglktndrkwcfegpe
eheilndsgetvkcrapggakkplrprwcdervssdqsalsefikfaegrr

Timeline for d1yksa2:

• d1yksa2 first appeared in SCOP 1.73
  
• d1yksa2 appears in SCOPe 2.05
  
• d1yksa2 appears in SCOPe 2.07
  
• d1yksa2 appears in the current release, SCOPe 2.08