Lineage for d1yhoa_ (1yho A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2903429Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2903430Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2903431Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 2903757Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. 2903805Species Human (Homo sapiens) [TaxId:9606] [53607] (80 PDB entries)
  8. 2903901Domain d1yhoa_: 1yho A: [123179]
    automated match to d1kmva_
    complexed with ndp, trr

Details for d1yhoa_

PDB Entry: 1yho (more details)

PDB Description: solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d1yhoa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1yhoa_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1yhoa_:

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Timeline for d1yhoa_: