SCOP 1.75: Domain d1ygyb1: 1ygy B:99-282

Lineage for d1ygyb1 (1ygy B:99-282)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.4: Formate/glycerate dehydrogenases, NAD-domain [51830] (10 proteins)
   this domain interrupts the other domain which defines family

6. Protein Phosphoglycerate dehydrogenase [51839] (2 species)
   has additional C-terminal domain of the ferredoxin fold

7. Species Mycobacterium tuberculosis [TaxId:1773] [141927] (1 PDB entry)
   Uniprot P0A544 98-281

8. Domain d1ygyb1: 1ygy B:99-282 [123154]
   Other proteins in same PDB: d1ygya2, d1ygya3, d1ygya4, d1ygyb2, d1ygyb3, d1ygyb4
   automatically matched to 1YGY A:99-282
   complexed with tar

Details for d1ygyb1

PDB Entry: 1ygy, 2.3 Å

PDB Description: crystal structure of d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis

PDB Compounds: (B:) D-3-phosphoglycerate dehydrogenase

SCOP Domain Sequences for d1ygyb1:

Sequence; same for both SEQRES and ATOM records:

>d1ygyb1 c.2.1.4 (B:99-282) Phosphoglycerate dehydrogenase {Mycobacterium tuberculosis [TaxId: 1773]}
nihsaaehalalllaasrqipaadaslrehtwkrssfsgteifgktvgvvglgrigqlva
qriaafgayvvaydpyvsparaaqlgiellslddllaradfisvhlpktpetaglidkea
laktkpgviivnaargglvdeaaladaitgghvraagldvfatepctdsplfelaqvvvt
phlg

Timeline for d1ygyb1:

• d1ygyb1 first appeared in SCOP 1.73
  
• d1ygyb1 appears in SCOPe 2.01
  
• d1ygyb1 appears in the current release, SCOPe 2.08