SCOPe 2.01: Domain d1y8nb1: 1y8n B:128-229

Lineage for d1y8nb1 (1y8n B:128-229)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.84: Barrel-sandwich hybrid [51229] (4 superfamilies)
   sandwich of half-barrel shaped beta-sheets

4. Superfamily b.84.1: Single hybrid motif [51230] (2 families)
   7 to 8 strands in 2 beta-sheets

5. Family b.84.1.1: Biotinyl/lipoyl-carrier proteins and domains [51231] (7 proteins)

6. Protein Lipoyl domain of dihydrolipoamide acetyltransferase [51238] (5 species)
   component of the pyruvate dehydrogenase complex

7. Species Human (Homo sapiens) [TaxId:9606] [51242] (4 PDB entries)

8. Domain d1y8nb1: 1y8n B:128-229 [122758]
   Other proteins in same PDB: d1y8na1, d1y8na2
   automatically matched to d1fyc__
   complexed with k, red

Details for d1y8nb1

PDB Entry: 1y8n, 2.6 Å

PDB Description: Crystal structure of the PDK3-L2 complex

PDB Compounds: (B:) Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

SCOPe Domain Sequences for d1y8nb1:

Sequence, based on SEQRES records:

>d1y8nb1 b.84.1.1 (B:128-229) Lipoyl domain of dihydrolipoamide acetyltransferase {Human (Homo sapiens) [TaxId: 9606]}
sypphmqvllpalsptmtmgtvqrwekkvgeklsegdllaeietdkatigfevqeegyla
kilvpegtrdvplgtplciivekeadisafadyrptevtdlk

Sequence, based on observed residues (ATOM records):

>d1y8nb1 b.84.1.1 (B:128-229) Lipoyl domain of dihydrolipoamide acetyltransferase {Human (Homo sapiens) [TaxId: 9606]}
sypphmqvllpalsptmtmgtvqrwekkvgeklsegdllaeietdkatigfevqeegyla
kilvpegtrdvplgtplciivekeadisafadytdlk

Timeline for d1y8nb1:

• d1y8nb1 first appeared in SCOP 1.73
  
• d1y8nb1 appears in SCOP 1.75
  
• d1y8nb1 appears in SCOPe 2.02
  
• d1y8nb1 appears in the current release, SCOPe 2.08, called d1y8nb_