Lineage for d1y18h1 (1y18 H:1-113)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2739519Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2739730Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2739899Species Human (Homo sapiens), cluster 3 [TaxId:9606] [88547] (30 PDB entries)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3)
  8. 2739963Domain d1y18h1: 1y18 H:1-113 [122533]
    Other proteins in same PDB: d1y18a1, d1y18a2, d1y18b2, d1y18c1, d1y18c2, d1y18d2, d1y18e1, d1y18e2, d1y18f2, d1y18h2, d1y18l1, d1y18l2
    automatically matched to d1aqkh1
    complexed with cl, han; mutant

Details for d1y18h1

PDB Entry: 1y18 (more details), 2.8 Å

PDB Description: fab fragment of catalytic elimination antibody 34e4 e(h50)d mutant in complex with hapten
PDB Compounds: (H:) Catalytic antibody 34E4 heavy chain

SCOPe Domain Sequences for d1y18h1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1y18h1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Human (Homo sapiens), cluster 3 [TaxId: 9606]}

SCOPe Domain Coordinates for d1y18h1:

Click to download the PDB-style file with coordinates for d1y18h1.
(The format of our PDB-style files is described here.)

Timeline for d1y18h1: