SCOP 1.75: Domain d1xrta2: 1xrt A:56-365

Lineage for d1xrta2 (1xrt A:56-365)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (18 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain [75073] (5 proteins)

6. Protein Two-domain dihydroorotase [141803] (1 species)

7. Species Aquifex aeolicus [TaxId:63363] [141804] (2 PDB entries)
   Uniprot O66990 56-365

8. Domain d1xrta2: 1xrt A:56-365 [122259]
   Other proteins in same PDB: d1xrta1, d1xrtb1
   automatically matched to 1XRF A:56-365
   complexed with zn

Details for d1xrta2

PDB Entry: 1xrt, 1.61 Å

PDB Description: The Crystal Structure of a Novel, Latent Dihydroorotase from Aquifex Aeolicus at 1.7 A Resolution

PDB Compounds: (A:) dihydroorotase

SCOP Domain Sequences for d1xrta2:

Sequence, based on SEQRES records:

>d1xrta2 c.1.9.6 (A:56-365) Two-domain dihydroorotase {Aquifex aeolicus [TaxId: 63363]}
gfidihvhlrdpgqtykediesgsrcavaggfttivcmpntnppidnttvvnyilqksks
vglcrvlptgtitkgrkgkeiadfyslkeagcvaftddgspvmdssvmrkalelasqlgv
pimdhceddklaygvinegevsallglssrapeaeeiqiardgilaqrtgghvhiqhvst
klsleiieffkekgvkitcevnpnhllfterevlnsganarvnpplrkkedrlaliegvk
rgiidcfatdhaphqtfekelvefampgiiglqtalpsalelyrkgiislkkliemftin
pariigvdlg

Sequence, based on observed residues (ATOM records):

>d1xrta2 c.1.9.6 (A:56-365) Two-domain dihydroorotase {Aquifex aeolicus [TaxId: 63363]}
gfidihvhlrdpgqtykediesgsrcavaggfttivcmpntnppidnttvvnyilqksks
vglcrvlptgtitkgrkgkeiadfyslkeagcvaftddgspvmdssvmrkalelasqlgv
pimdhceddklayaeeiqiardgilaqrtgghvhiqhvstklsleiieffkekgvkitce
vnpnhlledrlaliegvkrgiidcfatdhaphqtgiiglqtalpsalelyrkgiislkkl
iemftinpariigvdlg

Timeline for d1xrta2:

• d1xrta2 first appeared in SCOP 1.73
  
• d1xrta2 appears in SCOPe 2.01
  
• d1xrta2 appears in the current release, SCOPe 2.08