SCOP 1.73: Domain d1xrfa2: 1xrf A:56-365

Lineage for d1xrfa2 (1xrf A:56-365)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (15 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain [75073] (5 proteins)

6. Protein Two-domain dihydroorotase [141803] (1 species)

7. Species Aquifex aeolicus [TaxId:63363] [141804] (2 PDB entries)

8. Domain d1xrfa2: 1xrf A:56-365 [122255]
   Other proteins in same PDB: d1xrfa1
   complexed with so4, zn

Details for d1xrfa2

PDB Entry: 1xrf, 1.65 Å

PDB Description: the crystal structure of a novel, latent dihydroorotase from aquifex aeolicus at 1.7 a resolution

PDB Compounds: (A:) dihydroorotase

SCOP Domain Sequences for d1xrfa2:

Sequence, based on SEQRES records:

>d1xrfa2 c.1.9.6 (A:56-365) Two-domain dihydroorotase {Aquifex aeolicus [TaxId: 63363]}
gfidihvhlrdpgqtykediesgsrcavaggfttivcmpntnppidnttvvnyilqksks
vglcrvlptgtitkgrkgkeiadfyslkeagcvaftddgspvmdssvmrkalelasqlgv
pimdhceddklaygvinegevsallglssrapeaeeiqiardgilaqrtgghvhiqhvst
klsleiieffkekgvkitcevnpnhllfterevlnsganarvnpplrkkedrlaliegvk
rgiidcfatdhaphqtfekelvefampgiiglqtalpsalelyrkgiislkkliemftin
pariigvdlg

Sequence, based on observed residues (ATOM records):

>d1xrfa2 c.1.9.6 (A:56-365) Two-domain dihydroorotase {Aquifex aeolicus [TaxId: 63363]}
gfidihvhlrdpgqtykediesgsrcavaggfttivcmpntnppidnttvvnyilqksks
vglcrvlptgtitkgrkgkeiadfyslkeagcvaftddgspvmdssvmrkalelasqlgv
pimdhaeeiqiardgilaqrtgghvhiqhvstklsleiieffkekgvkitcevnpnhlld
rlaliegvkrgiidcfatdhaphqtmpgiiglqtalpsalelyrkgiislkkliemftin
pariigvdlg

Timeline for d1xrfa2:

• d1xrfa2 is new in SCOP 1.73
  
• d1xrfa2 appears in SCOP 1.75
  
• d1xrfa2 appears in the current release, SCOPe 2.08