SCOP 1.75: Domain d1xqca1: 1xqc A:307-548

Lineage for d1xqca1 (1xqc A:307-548)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (29 PDB entries)
   Uniprot P03372 307-551

8. Domain d1xqca1: 1xqc A:307-548 [122233]
   automatically matched to d1qkta_
   complexed with aej; mutant

Details for d1xqca1

PDB Entry: 1xqc, 2.05 Å

PDB Description: x-ray structure of eralpha lbd bound to a tetrahydroisoquinoline serm ligand at 2.05a resolution

PDB Compounds: (A:) Estrogen receptor

SCOP Domain Sequences for d1xqca1:

Sequence, based on SEQRES records:

>d1xqca1 a.123.1.1 (A:307-548) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvplydlllemlda
hr

Sequence, based on observed residues (ATOM records):

>d1xqca1 a.123.1.1 (A:307-548) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilysesmmglltnladrelvhminwakrvpgfvdltlhdqv
hllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdmllatssrfr
mmnlqgeefvclksiillnsgvytfstlksleekdhihrvldkitdtlihlmakagltlq
qqhqrlaqlllilshirhmsnkgmehlysmplydlllemldahr

Timeline for d1xqca1:

• d1xqca1 first appeared in SCOP 1.73
  
• d1xqca1 is called d1xqca_ in SCOPe 2.01
  
• d1xqca1 appears in the current release, SCOPe 2.08, called d1xqca_