SCOPe 2.04: Domain d1xnja3: 1xnj A:34-228

Lineage for d1xnja3 (1xnj A:34-228)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.4: Adenosine-5'phosphosulfate kinase (APS kinase) [52572] (2 proteins)
   automatically mapped to Pfam PF01583

6. Protein Adenosine-5'phosphosulfate kinase (APS kinase) [52573] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142215] (3 PDB entries)
   Uniprot O43252 34-228

8. Domain d1xnja3: 1xnj A:34-228 [122191]
   Other proteins in same PDB: d1xnja1, d1xnja2, d1xnjb1, d1xnjb2
   automated match to d1x6va3
   complexed with adp, adx

Details for d1xnja3

PDB Entry: 1xnj, 1.98 Å

PDB Description: aps complex of human paps synthetase 1

PDB Compounds: (A:) Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1

SCOPe Domain Sequences for d1xnja3:

Sequence, based on SEQRES records:

>d1xnja3 c.37.1.4 (A:34-228) Adenosine-5'phosphosulfate kinase (APS kinase) {Human (Homo sapiens) [TaxId: 9606]}
hvsrnkrgqvvgtrggfrgctvwltglsgagkttvsmaleeylvchgipcytldgdnirq
glnknlgfspedreenvrriaevaklfadaglvcitsfispytqdrnnarqihegaslpf
fevfvdaplhvceqrdvkglykkarageikgftgidseyekpeapelvlktdscdvndcv
qqvvellqerdivpv

Sequence, based on observed residues (ATOM records):

>d1xnja3 c.37.1.4 (A:34-228) Adenosine-5'phosphosulfate kinase (APS kinase) {Human (Homo sapiens) [TaxId: 9606]}
hvsrnkrgqvvgtrggfrgctvwltglsgagkttvsmaleeylvchgipcytldgdnirq
glnknlgfspedreenvrriaevaklfadaglvcitsfispytqdrnnarqihegaslpf
fevfvdapeyekpeapelvlktdscdvndcvqqvvellqerdivpv

Timeline for d1xnja3:

• d1xnja3 first appeared in SCOP 1.73
  
• d1xnja3 appears in SCOPe 2.03
  
• d1xnja3 appears in SCOPe 2.05
  
• d1xnja3 appears in the current release, SCOPe 2.08