Lineage for d1xn3c1 (1xn3 C:45P-385)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 803906Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 803907Superfamily b.50.1: Acid proteases [50630] (3 families) (S)
  5. 804499Family b.50.1.2: Pepsin-like [50646] (10 proteins)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 804554Protein beta-secretase (memapsin) [50671] (1 species)
  7. 804555Species Human (Homo sapiens) [TaxId:9606] [50672] (51 PDB entries)
    Uniprot P56817 58-446
    Uniprot P56817 60-447
    Uniprot P56817 58-446 ! Uniprot P56817 60-447
  8. 804591Domain d1xn3c1: 1xn3 C:45P-385 [122184]
    automatically matched to d1fkna_
    complexed with sta

Details for d1xn3c1

PDB Entry: 1xn3 (more details), 2 Å

PDB Description: Crystal structure of Beta-secretase bound to a long inhibitor with additional upstream residues.
PDB Compounds: (C:) Beta-secretase 1

SCOP Domain Sequences for d1xn3c1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1xn3c1 b.50.1.2 (C:45P-385) beta-secretase (memapsin) {Human (Homo sapiens) [TaxId: 9606]}
gsfvemvdnlrgksgqgyyvemtvgsppqtlnilvdtgssnfavgaaphpflhryyqrql
sstyrdlrkgvyvpytqgkwegelgtdlvsiphgpnvtvraniaaitesdkffingsnwe
gilglayaeiarpddslepffdslvkqthvpnlfslqlcgagfplnqsevlasvggsmii
ggidhslytgslwytpirrewyyeviivrveingqdlkmdckeynydksivdsgttnlrl
pkkvfeaavksikaasstekfpdgfwlgeqlvcwqagttpwnifpvislylmgevtnqsf
ritilpqqylrpvedvatsqddcykfaisqsstgtvmgavimegfyvvfdrarkrigfav
sachvhdefrtaavegpfvtldmedcgyn

SCOP Domain Coordinates for d1xn3c1:

Click to download the PDB-style file with coordinates for d1xn3c1.
(The format of our PDB-style files is described here.)

Timeline for d1xn3c1: